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Where is pain with ankylosing spondylitis? Pain and stiffness. Ankylosing spondylitis often starts around the sacroiliac joints, where the sacrum (the lowest major part of the spine) joins the ilium bone of the pelvis in the lower back region. It might hurt more at night and get better when you wake up.
What is the best treatment for ankylosing spondylitis? Medications. Nonsteroidal anti-inflammatory drugs (NSAIDs) — such as naproxen (Naprosyn) and indomethacin (Indocin) — are the medications doctors most commonly use to treat ankylosing spondylitis. They can relieve your inflammation, pain and stiffness. However, these medications might cause gastrointestinal bleeding.
Does spondylitis cause fatigue? Fatigue can be caused by many things related to spondylitis such as loss of sleep because of physical discomfort, as well as uncontrolled pain. Anemia may also contribute to a feeling of tiredness. Treating the inflammation caused by spondylitis can assist in decreasing fatigue and anemia.
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